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Physics Seminar

Mechanics of membrane during clathrin-mediated endocytosis

Speaker: Prof Rui Ma (Xiamen University)
Date: Wednesday 13 January 2021
Time: 15:00 in UK
Venue: Zoom

Clathrin-mediated endocytosis is a fundamental process for cells to internalize materials from outside to inside. During this process, a patch of flat plasma membrane is deformed into a vesicle. In this talk, I will present our recent work on how to pull a flat membrane into a tubular shape against high turgor pressure in walled cells. The vesiculation mechanisms of membrane will also be discussed. By comparing with experimental results, our theoretical work helps answer questions that are hard to address by experiments, such as the magnitude of forces actin polymerization needs to provide during clathrin-mediated endocytosis in yeast cells.